IMPROVING THE QUALITY OF HUMAN LIFE WITH HELP OF STEM CELL SCIENCE GIOSTAR
GIOSTAR Awarded As 50 Most Influential Companies Of The Year 2021
The concept of regenerative medicine using the body’s stem cells and growth factors to repair tissues may become a reality as new basic science works and initial clinical experiences have “teamed up” to develop alternative therapeutic strategies to treat various previously untreatable diseases. Stem cells have tremendous promise to help us understand and treat a range of diseases, injuries, and other health-related conditions. Necessary clinical trials involving stem cells are underway for many different conditions, and researchers continue to explore new avenues using stem cells in medicine.
Some companies worldwide have not limited the use of stem cell therapy to just research and have been using ethically sourced stem cells to treat many health problems, from diseases to cancer. One of the global leaders in stem cell therapy and research is the Global Institute of Stem Cell Therapy and Research (GIOSTAR). GIOSTAR was formed with the vision to provide stem cell-based therapy to aid those suffering from degenerative or genetic diseases around the world. GIOSTAR can treat several devastating immunological disorders and blood-related diseases.
Blood donation camp & Free Ortho OPD Camp organized by GIOSTAR Chandigarh Branch on 13th Nov 2021. Camp was opened by Chief Guest Kulwant Singh Ex Mayor Mohali City. & Guest of Honour Dr. Seemha Rai Chairperson Centre of Stem cell, Tissue engineering & Bio Medical Excellence Panjab University. Around 84 Blood Donors donate their Blood in this camp.
1st International Conference on Medicine and Research (ICMR-21)
Topic : Role of Stem Cell in Covid-19
Dr. Srivastava is a Chairman and Cofounder of the California-based Global Institute of Stem Cell Therapy and Research (GIOSTAR) headquartered in San Diego, California (USA). Several governments and organizations – including the United States, India, China, Turkey, Kuwait, Thailand, Philippines, Bahamas, Saudi Arabia and many others
seek his advice and guidance on drafting their strategic and national policy formulations and program directions in the area of stem cell research, development, and its regulations.
The company was formed with the vision to provide stem cell based therapy to aid those suffering from degenerative or genetic diseases around the world such as Parkinson’s disease, Alzheimer’s disease, neuropathy, diabetes, heart disease, stroke, spinal cord injuries, paralysis, and blood related diseases. GIOSTAR is a leader in developing the most advanced stem cell based technology, supported by leading scientists with pioneering publications in the area of stem cell biology. The company’s primary focus is to discover and develop a cure for human diseases, with state-of-theart, unique stem cell based therapies and products. Regenerative medicine provides promise for treatments of diseases previously regarded as incurable.
Under Dr. Srivastava’s creative leadership, a group of esteemed scientists and clinicians are developing stem cell therapies for various types of autoimmune diseases and blood disorders.
Dr. Anand Srivastava has been associated with leading universities and research institutions throughout the world. In affiliation with University of California San Diego (UCSD) School of Medicine, University of California Irvine (UCI) School of Medicine, The Salk Institute for Biological Studies in San Diego, The Sanford Burnham Prebys Medical Discovery Institute, and University of California, Los Angeles (UCLA) School of Medicine, Dr. Srivastava has developed several research projects. He has extensive research experience in the field of stem cells, which is documented by several publications in revered scientific journals.
California, United States Dr. ANAND Srivastava, MS,
Top 10 Influential Entrepreneurs in Healthcare 2021
GIOSTAR is a San Diego, California-based organization led by Dr. Anand Srivastava and Deven Patel. Dr. Srivastava has held scientific positions at leading universities and research institutions in the United States, such as the University of California Irvine and UC Los Angeles, along with the following San Diego-based institutions: Salk Institute for Biological Studies, Sanford Burnham Prebys Medical Discovery Institute. He has authored more than 100 scientific publications, and is widely regarded as the “father of stem cell science.” Under his leadership, GIOSTAR has been one of the pioneers in the field of stem cell therapy. Few in the scientific community were willing to accept the therapeutic efficacy of stem cells, despite the publication of numerous studies providing supporting evidence. In contrast to these skeptics, GIOSTAR joined the leading groups of scientists and researchers in embracing the science and sought to build upon its compendium of findings.
GIOSTAR’s vision is to provide its scientific and medical expertise to establish the most advanced stem cell therapy and research institutes around the world. The company actively seeks public and private sector investors to help deliver stem cell-based therapies to people suffering from degenerative or genetic diseases. GIOSTAR is in the process of expanding its operations in the US, India, China, Thailand, Philippines, Japan, Australia, Singapore, Brazil, Bahamas, and a few more countries.
What were the constraints you faced at the time of inception?
GIOSTAR faced several ethical and financial constraints at the inception of the company, and for a few years thereafter. As the primary findings in the field were based on embryonic stem cells, social and ethical groups vehemently opposed the use of stem cells for research and therapy. These objections culminated in restrictions on fundings from government agencies. However, scientists demonstrated that stem cells could be isolated from adult tissues, paving the way for extensive research and the application of the science for therapeutic purposes. Since most of the therapeutic interventions in conventional medicine are palliative (i.e., they only help manage symptoms), it was difficult for people to accept that any therapy could be curative, a capability uniquely afforded by stem cells.
What unique services do you provide to the customers?
GIOSTAR has several unique characteristics that distinguish us from our peers. Our Institute has been the pioneer in the research field of stem cell science, with a firm commitment to staying abreast of the latest developments with this technology. Second, we want to offer our patients comprehensive therapeutic help, which is thoroughly tested in our numerous clinics. Finally, our services are rooted in an altruistic, humanitarian mission to help the masses, as opposed to an opportunistic quest to derive monetary gain from patients’ suffering.
Why should one prefer you?
GIOSTAR delivers therapies that are customized to each patient’s health conditions, grounded in decades of logical, scientific research. We evaluate the body as a cohesive unit, as opposed to a disjointed collection of organs and ailments. This holistic perspective enables us to devise and deliver the most effective therapies.
What personality traits and capabilities do you believe are required to enhance and promote health solution providing services?
Certain characteristics are essential for success in any field. Healthcare, in particular, requires that its practitioners possess an unyielding dedication to the well-being of all humans. GIOSTAR takes this commitment very seriously and approaches healthcare in a highly integrated manner, as opposed to the traditional compartmentalized perspective. This practice, coupled with the use of stem cells, enables us to devise the most effective therapies to manage the myriad of health problems of our patients. Share about your journey from the beginning. Our professional journey began with the recognition of the potential for stem cells to serve as a highly effective therapeutic agent for treating several degenerative diseases. In beginning, our firm had to overcome a great deal of skepticism about the efficacy of this GIOSTAR Influential Entrepreneurs in Healthcare, Top 10 2021 Dr. Anand Srivastava Chairman & Co-founder technology. However, scientists and those in the general community alike began expressing great enthusiasm after experiencing the therapeutic wonders of science first-hand. This led to GIOSTAR and other leading stem cell institutions receiving steadily increasing recognition.
How do you manage the promotion of your project through social media outreach and email campaigns?
GIOSTAR relies primarily on word-of-mouth referrals to augment our patient base. After they experience dramatic positive results following the treatments in our global facilities, patients frequently refer friends, family members, and other loved ones to GIOSTAR. Given our impressive success rate, they feel that our firm is uniquely positioned to provide therapeutic benefit to those suffering from the most debilitating disorders.
What do you think about the expansion of GIOSTAR? What will be the plan?
At present, our clinics are in India and Mexico. We are in negotiations with business groups for further expansion in Japan, Thailand, South Africa, and several other countries.
How do you see the future of healthcare in nearby times?
A thorough re-evaluation of our medical system is needed, on numerous fronts: Financial. The cost of training medical professionals is increasing exponentially every year, which may result in a severe shortage of well-trained medical professionals. Coupled with the exorbitant investments required for developing new therapeutic agents, effective medical care will likely become cost prohibitive for most patients. Holistic Approach. Currently, healthcare in the United States is focused primarily on interventions that “buy some time” for the body to heal; in other words, not many interventions are truly curative. Therapies are currently geared toward specific diseases and treat organs as individual, disconnected compartments of the body. Because of this narrow focus, modern medicine has been ineffective in treating metabolic diseases. Healthcare professionals should instead view the entire body as a unit, and devise therapies accordingly; this approach will pave the way for cures for metabolic diseases. As we know, cells are the unit of life and stem cells are the master cells. Hence, these cells are aptly suited to repair damaged organs in a very holistic manner. In our scientific view, stem cells are the least expensive and the best way to manage several metabolic diseases.
Can you describe emerging trends you noticed HEALTHCARE industry?
The most significant change we’ve observed in healthcare is the super specialization of medical professionals. The side effects of the trend of superspecialization are adversely affecting the availability of health care personnel as so super-specialized persons may be fewer and fewer. Additionally, the extensive investment of time and money into super-specialized training will likely dissuade intelligent, capable individuals from entering the health care profession. In addition, clinicians are inclining more towards the holistic approach to managing a metabolic disease and not treating a disease just blocking a signaling pathway which often comes up with several side effects.
Please tell us if there is an effective solution to the current COVID-19 scenario? Coronavirus, which causes COVID-19, induces severe inflammation and lung damage. This can be effectively managed by using a specific category of stem cells known as mesenchymal stem cells (MSCs). These cells are well-known for their capabilities for immunomodulatory function and tissue regeneration, thus providing a two-pronged approach for battling COVID-19. Therefore, MSCs provide the best clinical option for managing COVID-19 symptoms and related organ damage. Based on these facts, GIOSTAR procured approval from the United States Food and Drug Administration (FDA) for using stem cells for COVID-19 patients under the FDA “expanded access for compassionate use” program. The company was then able to successfully treat patients who were gravely ill with the disease.
Year of Founding : 2008
Funding Information : Mostly research grants.
Founding Members : Dr. Anand Srivastava and Mr. Deven Patel
Office Locations : 4660 La Jolla Village Drive Suite 100 & 200 San Diego, California, 92122, U.S.A. (headquarters)
GIOSTAR Launches Subsidiary to Combat COVID-19 and Long COVID
Stem cell research institute seeks to ramp up the charge against global pandemic
SAN DIEGO, May 5, 2021 /PRNewswire/ — Global Institute of Stem Cell Therapy and Research (GIOSTAR), the worldwide leader in regenerative technologies, is pleased to announce the formation of GIOCOV. The company – launched in tandem with TAG Investment Bankers LTD of London (TAG) – is a wholly-owned subsidiary aimed at delivering stem cell-based treatments for the acute phase of COVID-19, along with the chronic phase (known as Long COVID).
A Long Haul for Millions
As of May 2021, roughly 280 million individuals have been fully vaccinated against COVID-19. The worldwide rollout has helped contain the impact and reduce the high morbidity rates of the disease – which has claimed more than 3 million lives. However, data reveals that, even after recovering from COVID-19, many patients continue experiencing a compendium of debilitating symptoms known collectively as Long COVID.
These “long-haulers” may experience one or both of the following:
Symptoms experienced throughout the course of COVID-19: fatigue, cognitive impairment (brain fog), difficulty breathing, headaches, difficulty exercising, depression, sleep difficulty, loss of sense of taste or smell
New symptoms: hair loss, anxiety, and heart problems
In a study conducted by the Centers for Disease Control (CDC), roughly 1 in 3 patients (including both mild and severe cases) observed suffered from highly debilitating symptoms of COVID-19 several weeks after their diagnosis. Even more alarming, a University of Leicester investigation found that 7 in 10 patients hospitalized for COVID-19 didn’t fully recover 5 months after discharge. These grim statistics point to a dire global health crisis, with enormous projected costs of management.
“Long COVID is very serious,” noted World Health Organization (WHO) Director-General Tedros Adhanom Ghebreyesus. “To a significant number of people, this virus poses a range of serious long-term effects. The symptoms people have to endure are very debilitating, leading many to be unable to work and function properly.” Long COVID issues may ultimately culminate in chronic disease, requiring sharply increased levels of medication, long-term hospitalization, and debilitating lifestyle changes that will likely lead to premature death.
Extending the Impact of Novel Therapeutic Approach
GIOSTAR has played a central role in the fight against COVID-19. The US Food and Drug Administration (FDA) granted the firm FDA Approval Under Compassionate Use (Expanded Access Program) to treat COVID-19 patients – making GIOSTAR one of the first companies in the world to obtain this credential. Leveraging proprietary scientific protocols and techniques developed by Chairman and Co-Founder Dr. Anand Srivastava, GIOSTAR succeeded in treating several critically ill COVID patients using stem cells.
“The anti-inflammatory capabilities of stem cells make them an excellent therapeutic agent,” explained Dr. Srivastava. “Further, their ability to differentiate into myriad cells helps to restore organ function, thereby enabling [patient] recovery from the post-COVID-19 syndrome.”
GIOSTAR is looking to build upon its success in addressing the acute phase of COVID-19. With the launch of GIOCOV, the company is now pursuing the fully licensed status of stem cell treatment for COVID and Long COVID patients in the United States (US), United Kingdom (UK), and the European Union (EU). This goal will require completion of clinical trials to establish treatment protocols and secure full approval from FDA, Medicines and Healthcare products Regulatory Agency (MHRA), and European Medicines Agency (EMA) – the regulatory bodies for the US, UK, and EU respectively. Upon receiving this, GIOCOV seeks to gain acceptance from healthcare authorities, providers, and insurers alike for reimbursement of treatment costs.
“GIOCOV’s aim is to provide cost-effective treatment for all Long COVID sufferers worldwide,” noted GIOSTAR CEO and Co-Founder Deven Patel. “This will show huge cost-benefit against the cost of long-term medication and hospitalization and provide enhanced quality of life to patients all over the globe.” Given the results of the aforementioned study, more than 100 million long-haulers (representing 70% of the over 150 million total COVID 19 cases) stand to achieve enormous economic and health-related benefits from this initiative.
To realize these goals GIOSTAR – in collaboration with their advisors TAG Investment Bankers Ltd of London – intends for GIOCOV to raise funds to carry out the necessary trials through a listing on the London Stock Exchange (LSE), Nasdaq, and other stock exchanges. GIOSTAR also aims to secure funding from suitable grants.
GIOSTAR is pleased to officially announce its pre-IPO fundraising round, the details of which are available at the TAG Investment Bankers Website: https://twex.ch/giocov/
GIOSTAR is the pioneer and established leader in the field of stem cell science and regenerative medicine. Based in San Diego, California, USA, the company’s primary aim is to develop treatments for the masses suffering from metabolic and degenerative diseases around the globe.
GIOSTAR is a coalition of world-class scientists, physicians, and entrepreneurs in the field of stem cell science. The team members have been involved for the last 20 years in the development and utilization of stem cell-based clinical protocols related to degenerative, malignant, and non-malignant disorders. The adult stem cell technology is well developed and has been used regularly in the Institute’s clinical practice to treat many patients.
COO at TAG Investment Bankers Ltd
Tel: +44 7801 413597
GIOSTAR Reports on a Positive Outcome of a COVID-19 Patient After Stem Cell Treatment
Promising results point to a potential alternative in combating the pandemic
SAN DIEGO, July 21, 2020 /PRNewswire/ — Global Institute of Stem Cell Therapy and Research (GIOSTAR), the worldwide leader in stem cell research, is pleased to announce the outcome of a COVID-19 patient treated using stem cells. Led by Chairman and Co-Founder Dr. Anand Srivastava, GIOSTAR received approval for the treatment under the U.S. Food and Drug Administration (FDA) “expanded access for compassionate use” program. As of July 14, 2020, there have been more than 13 million COVID-19 cases and over 500,000 deaths worldwide.
Contending with a Grim Prognosis
Under the direction of GIOSTAR Medical Director Dr. Prabhat Soni, a 53-year old male patient suffering from COVID-19 pneumonia was admitted to Saint Michael’s Medical Center in Newark, New Jersey, under the care of Dr. Richard Miller, MD, Chairman, Department of Pulmonary Medicine. The patient’s condition worsened over the course of the standard treatments, along with convalescent plasma therapy. He went into septic shock and his renal and hepatic functions continued to decline, requiring dialysis. The patient suffered a stroke, and remained in a coma at Saint Michael’s intensive care unit (ICU).
Improved Outcomesfroman Alternative Strategy
Noting the limited effectiveness of these measures, Dr. Soni designed a plan to treat the patient using stem cells. Research physician Dr. Michael J. DeMarco coordinated the plan, with day-to-day care provided to the patient by Dr. Miller and his Critical Care fellows Dr. Rutwik Patel and Dr. Harish Sharma, at Saint Michael’s.
Following treatment with AlloRx Stem Cells® from Vitro Biopharma, a Colorado-based company, the patient began recovery from multiple organ failure and a coma of almost 7 weeks. He had excellent recovery of his pulmonary, liver, and renal functions, ultimately coming off dialysis and ventilator support.
The patient’s recovery of neuro-muscular functions is evident in improved clarity of speech, ease of swallowing food, and many other everyday functions. Additionally, the elevated levels of inflammation markers seen prior to stem cell therapy have come down to within normal range. The patient was finally discharged from ICU, and is undergoing physical therapy with strong hopes of complete recovery.
COVID-19 and Mesenchymal Stem Cells (MSCs)
COVID-19 infection leads to uncontrolled release of proinflammatory cytokines – known as “cytokine storms” – that potentially leads to fatal damage of many organs of the body. “MSCs have specific characteristics that, when infused in the bloodstream,” explained Dr. Srivastava, “neutralize proinflammatory cytokines (through ‘immunomodulation’), down-regulate the inflammatory gene actions and send messages to regenerate damaged lung and other tissues, which may help in managing COVID-19.”
Next Steps for Treatment of COVID-19
“We got outstanding results after using MSCs on our first patient,” noted Dr. Soni, “with similar results being reported by other institutions.” Dr. Srivastava states that “the use of MSCs may be a great option not only for critically ill COVID-19 patients, but also for those who may have risk of exposure. MSCs may prevent people from aggravations of the infection, thereby potentially saving lives while lowering the load on hospitals and the economy.” Drs. Srivastava and Soni emphasize that a placebo-controlled, double-blind study would be needed to better understand the measurable outcome of stem cell treatment for COVID-19.
GIOSTAR is the pioneer and established leader in the field of stem cell research. Under the leadership of Co-Founders Dr. Anand Srivastava and Mr. Deven Patel, the San Diego-based Institute has a tradition of groundbreaking research in stem cell science spanning over two decades.