Stem cell treatment of Spinal muscular atrophy (SMA)
Spinal Muscular Atrophy (SMA) is a neuromuscular disease characterized by degeneration of motor neurons, resulting in progressive muscular atrophy (wasting away) and weakness. The clinical spectrum of SMA ranges from early infant death to normal adult life with only mild weakness. These patients often require comprehensive medical care involving multiple disciplines, including pediatric pulmonology, pediatric neurology, pediatric orthopaedic surgery, pediatric critical care, and physical medicine and rehabilitation; and physical therapy, occupational therapy, respiratory therapy, and clinical nutrition.
In all of its forms, the primary feature of SMA is muscle weakness, accompanied by atrophy of muscle. This is the result of denervation, or loss of the signal to contract, that is transmitted from the spinal cord. This is normally transmitted from motor neurons in the spinal cord to muscle via the motor neuron’s axon, but either the motor neuron with its axon, or the axon itself, is lost in all forms of SMA.
The features of SMA are strongly related to its severity and age of onset. SMA caused by mutation of the SMN gene has a wide range, from infancy to adult, fatal to trivial, with different affected individuals manifesting every shade of impairment between these two extremes. Many of the symptoms of SMA relate to secondary complications of muscle weakness. GIOSTAR has developed the techniques to differentiate the Stem cells into the high purity motor neuron progenitor cells. These cells have ability to regenerate the new and healthy neurons after transplantation and may cure the disease.
What Sets Us Apart
- Headquartered in USA.
- The founder is leading stem cell scientist credited with helping in setting up the stem cell research labs at top research institutions in the US including Salk Research Institute, Sanford-Burnham Institute, UCI, UCSD.
- Medical Advisory Board comprising of luminaries who have worked at University of California, San Diego (UCSD), University of California Irvine (UCI), Imperial College, London.
- Endorsed by Honourable Prime Minister of India.
- State of the art and an only private hospital in India inaugurated by Prime Minister.
- World’s Largest Stem Cell Hospital funded by the government of India.
Disclaimer : Results may vary for each patient. GIOSTAR practice the application of stem cell therapy within the legal regulations of each country.