Dr Anand Talk at People’s Unlimited Phoenix, Arizona
Dr. Anand Srivastava’s new publication on Inflammatory Bowel Diseases: Current Therapeutic Approaches and Potential of using Stem Cells
Theme: Co-creating a New Future of Biomedicine
Time: November 9-11, 2017 Place: Xi’an, China
Dear Dr. Anand Srivastava,
We are proud to announce that The World Congress of Biomedical Engineering-2017 (WCBME-2017) with a theme of “Co-creating a New Future of Biomedicine”, will be held during 9 to 11 November, 2017, Xi’an, China. On behalf of the organizing committee, we cordially welcome you to join us as a speaker at Session 6-3: Tissue Repair and Regenerative Medicine.
If the suggested thematic session is not your current focused core, you may look through the whole sessions and transfer another one that fit your interest (more info about the program is available at http://www.bitcongress.com/wcbme2017/programlayout.asp
BIT’s 1 st World Congress of . Bio medical Engineering 2017. Time: November 9-11, 2017 Place: Xi’an, China . Chapter 1: Main Conference
WCBME-2017 features a very strong technical program, mainly focused on: Biomechanics and Mechanobiology, Biomedical Imaging, Biomaterials, Biosensors and Bioelectronics, Cell and Tissue Engineering, Nanomedicine, Biomedical Optics, and cutting-edge Biomedical Instrumentation and Devices. It aims to provide a platform for all experts from academia, industry and national labs to discuss latest hot researches and achievements. Attendees will hear world-class speakers discussing the challenges and opportunities facing the biomedical engineering field. The business & academic experts who are from home and abroad will give excellent speeches.
In addition to the dynamic scientific program, you will benefit from the wonderful experience in Xi’an, China. Xi’an is the oldest of the Four Great Ancient Capitals, having held the position under several of the most important dynasties in Chinese history. We hope you will enjoy your stay in this beautiful city with all its feature, beauty, architecture and hospitality!
PS: We expect your precious comments or suggestions on the structure of our program, as well as your reference to other speakers that will be highly appreciated. We look forward to receiving your replies on the following questions:
For more information, please visit the conference website http://www.bitcongress.com/wcbme2017/default.asp
We look forward to seeing you in Xi’an in 2017 for this influential event!
Ms. Joyce Tan
Organizing Committee of WCBME2017
Add: East Wing, F11, Building 1,
Dalian Ascendas IT Park, 1 Hui Xian Yuan,
Dalian Hi-tech Industrial Zone,
Title: Down-regulation of epithelial membrane protein-1 is associated with HNSCC cell proliferation
Journal: Experimental and Molecular Pathology
Corresponding Author: Zezhang Tao
Co-authors: Yang Xiling, Wang Lei, Hu Zhangwei, Xu Yong, Zheng Anyuan, Li Fen, Xiao Bokui, Chen Chen
Dear Dr Srivastava,
I would like to invite you to review the above-referenced manuscript. To maintain our journal’s high standards we need the best reviewers, and given your expertise in this area I would greatly appreciate your contribution.
I kindly ask you to give this review invitation the same consideration that you would want one of your own manuscripts to receive. Please find the abstract of the manuscript at the end of this email.
|If you are willing to review this manuscript, please click on the link below:|
Please also note that authors have been invited to convert their supplementary material into a Data in Brief article (a data description article). You may notice this change alongside the revised manuscript. You do not need to review this, but may need to look at the files in order to confirm that any supporting information you requested is present there.
I look forward to receiving your response.
Experimental and Molecular Pathology
To investigate epithelial membrane protein-1 (EMP1) gene function in Head and Neck Squamous Cell Carcinoma (HNSCC) tumorigenesis and development. We first used GEO dataset to analyze the EMP1 gene expression in HNSCC. Second, we investigated the EMP1 protein expression in tissue microassay to analyze the relationship between EMP1 protein expression and TNM stage. Third, the co-expression genes data of EMP1 were extracted from Cancer Cell Line Encyclopedia database(CCLE database) , and their correlation were analyzed in The Cancer Genome Atlas HNSCC database(TCGA HNSCC database). Next, the GO (Gene Ontology Analysis) and KEGG Pathway enrichment analysis were carried out. Finally, we overexpressed the EMP1 in HNSCC cell line Cal-27, protein expression were analyzed by Western blot respectively as well as cell viability and migration were evaluated by Cell Counting Kit-8 (CCK-8) and transwell chamber assay. Analysis of GEO dataset concluded that EMP1 gene is down-regulated in HNSCC tumor tissues compared with normal tissues (P<0.05). There was no statistically significant difference of EMP1 gene expression between different T-stage and N-stage tumor tissues (P>0.05). The results of TMA showed that EMP1 protein expression in tumor was lower than that in normal tissue (P<0.05). Expression of EMP1 protein was not correlated with TNM stage of HNSCC. In addition, The Cal-27 overexpressed EMP1 significantly decreased cell viability and the invasion significantly reduced (P<0.05). After EMP1 overexpression ITGA3 and EPHA2 genes were significantly up-regulated, while ANXA1 gene was significantly down-regulated. Our data demonstrated that EMP1 gene down-regulation involved in the HNSCC tumorigenesis and development. It may serve as a novel biomarker for prognostic evaluation of patients with HNSCC.
Free access to ScienceDirect and Scopus
To assist you with reviewing this manuscript it is our pleasure to offer you 30 days of free access to ScienceDirect and Scopus. Your complimentary access can be accessed at any time within 6 months of the day you accept this review invitation and will ensure that you can access ScienceDirect and Scopus both from home and via your institute. Just click on the ‘Go to Scopus’ tab on your main menu.
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